Evaluation of Protective Effects of Curcumin and Nanocurcumin on Aluminium Phosphide‑Induced Subacute Lung Injury in Rats: Modulation of Oxidative Stress through SIRT1/FOXO3 Signalling Pathway.

Mohammad Ali MahloojiAli HeshmatiNejat KheiripourHassan GhasemiSara Soleimani AslGhasem SolgiAkram Ranjbar Asieh Hosseini

Published in: Drug research (2021)

Nanocurcumin had a significantly more protective effect than curcumin to prevent AlP-induced lung injury via inhibition of oxidative stress. Nanocurcumin could be considered a suitable therapeutic choice for AlP poisoning.

Keyphrases

oxidative stress
diabetic rats
high glucose
ischemia reperfusion injury
dna damage
induced apoptosis
transcription factor
drug induced
endothelial cells
pi k akt
stress induced
endoplasmic reticulum stress