Fe 3 O 4 Magnetic Nanoparticles Under Static Magnetic Field Improve Osteogenesis via RUNX-2 and Inhibit Osteoclastogenesis by the Induction of Apoptosis.

Krzysztof MaryczPaulina Sobierajska Rafał Jakub Wiglusz Rafał Idczak Jean-Marie Nedelec Andrzej Mariusz Fal Katarzyna Kornicka

Published in: International journal of nanomedicine (2020)

nanoparticles together with magnetic field can be applied for the fabrication of novel biomaterials for the treatment of bone disorders related to bone loss in which a balance between bone-forming and resorbing cells is disturbed.

Keyphrases

bone loss
cell cycle arrest
magnetic nanoparticles
induced apoptosis
endoplasmic reticulum stress
cell death
bone regeneration
oxidative stress
pi k akt
tissue engineering
bone mineral density
cell proliferation
combination therapy
inflammatory response
body composition
postmenopausal women
drug induced
soft tissue