Cerebral nitric oxide and mitochondrial function in patients suffering aneurysmal subarachnoid hemorrhage-a translational approach.
Arthur HosmannNadja MilivojevSergiu DumitrescuAndrea ReinprechtAdelheid WeidingerAndrey V KozlovPublished in: Acta neurochirurgica (2020)
Exploratory analysis of our data suggests that during the acute phase of SAH, NO plays a key role in the neuronal damage impairing mitochondrial function and facilitating accumulation of mitochondrial substrate; further studies are required to understand mechanisms underlying this observation.