A selenoprotein T-derived peptide protects the heart against ischaemia/reperfusion injury through inhibition of apoptosis and oxidative stress.

C RoccaL BoukhzarM C GranieriI AlsharifR MazzaB LefrancB TotaJ LeprinceM C CerraYoussef Anouar Domenico Gabriele

Published in: Acta physiologica (Oxford, England) (2018)

These results unravel the role of SelT as a cardiac modulator and identify PSELT as an effective pharmacological post-conditioning agent able to protect the heart after ischaemic injury.

Keyphrases

oxidative stress
heart failure
atrial fibrillation
left ventricular
acute myocardial infarction
diabetic rats
cerebral ischemia
induced apoptosis
coronary artery disease
cell proliferation
percutaneous coronary intervention