Morphine-induced RACK1-dependent autophagy in immortalized neuronal cell lines.

Li-Tao LiuYing-Qi SongXue-Shen ChenYin LiuJie-Jun ZhuLi-Ming ZhouShi-Jun XuLi-Hong Wan

Published in: British journal of pharmacology (2020)

Our findings revealed a critical role for RACK1-dependent autophagy in morphine-promoted maintenance of CPP memory in mice and supported the notion that control of RACK1-dependent autophagic pathways may become an important target for novel therapeutics for morphine-associated memory.

Keyphrases

cell death
endoplasmic reticulum stress
oxidative stress
signaling pathway
working memory
diabetic rats
high glucose
type diabetes
adipose tissue
high fat diet induced
wild type