What contributes to disability in progressive MS? A brain and cervical cord-matched quantitative MRI study.

Carmen TurMarco BattistonMarios C YiannakasCollorone Sara Alberto CalviFerran PradosBaris KanberFrancesco GrussuAntonio RicciardiPatrizia PajakDaniele MartinelliTorben SchneiderOlga CiccarelliRebecca S SamsonClaudia Am Gandini Wheeler-Kingshott

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)

Fast brain-and-cord-matched qMRI protocols are feasible and identify demyelination - combined with other mechanisms - as key for disability accumulation in PMS.

Keyphrases

multiple sclerosis
white matter
resting state
magnetic resonance imaging
functional connectivity
mass spectrometry
high resolution
cerebral ischemia
contrast enhanced
magnetic resonance
diffusion weighted imaging