Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS).
Matthew E BerrySamantha M McCabeNeil C ShandDuncan GrahamKaren FauldsPublished in: Chemical communications (Cambridge, England) (2022)
A model for the prediction of the depth of two 'flavours' of surface enhanced Raman scattering (SERS) active nanotags embedded within porcine tissue is demonstrated using ratiometric analysis. Using a handheld spatially offset Raman (SORS) instrument, SESORS signals could be detected from nanotags at depths down to 48 mm for the first time using a backscattering SORS geometry.