One-year efficacy and safety of naloxegol on symptoms and quality of life related to opioid-induced constipation in patients with cancer: KYONAL study.

Manuel CoboCarmen Beato ZambranoLuis Cabezón-GutiérrezRodolfo Chicas-SettMaría Isabel Blancas López-BarajasFrancisco Javier García NavalónJosé Luis Fírvida PérezGala Serrano BermúdezPilar Togores TorresIgnacio Delgado MingoranceAlexandra Giraldo MarínAnna Librán OriolAlfredo Paredes LarioPedro Sánchez MauriñoOliver Higuera GómezDiana Moreno MuñozIbone Huerta GonzálezAlmudena Sanz-YagüeBegoña Soler-López

Published in: BMJ supportive & palliative care (2021)

The results of this first long-term and real-world-data study in patients with cancer, showed the sustained efficacy and safety of naloxegol for the treatment of OIC in this group of patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
chronic pain
peritoneal dialysis
physical activity
big data
depressive symptoms
artificial intelligence
patient reported outcomes
irritable bowel syndrome