Bradykinin and Galectin-3 in Survived and Deceased Patients with COVID-19 Pneumonia: An Increasingly Promising Biochemical Target.

Tamara Nikolic TurnicVišeslav PopadićSlobodan KlasnjaAna SekulicNovica NikolicVladimir ZivkovicNevena JeremicMarijana AndjicNevena DraginicIvan SrejovicJovana N Jeremić Marija Zdravković Jakovljevic Lj Vladimir

Published in: Oxidative medicine and cellular longevity (2022)

The present study strongly supports the bradykinin storm hypothesis. Since elevated bradykinin levels have been found in most COVID-19 cases with fatal outcomes, the future therapeutical strategies for COVID-19 have to be focused on reducing bradykinin serum concentrations.

Keyphrases

coronavirus disease
sars cov
respiratory syndrome coronavirus
type diabetes
current status
metabolic syndrome
kidney transplantation
adipose tissue
intensive care unit
community acquired pneumonia