Modulation of RAB7A Protein Expression Determines Resistance to Cisplatin through Late Endocytic Pathway Impairment and Extracellular Vesicular Secretion.
Flora GuerraAurora PaianoDanilo MigoniGiulia GirolimettiAnna Myriam PerronePierandrea De IacoFrancesco Paolo FanizziGiuseppe GasparreCecilia BucciPublished in: Cancers (2019)
We demonstrated, for the first time, that RAB7A regulates CDDP resistance determining alterations in late endocytic trafficking and drug efflux through extracellular vesicles.
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