Early ocular surface and tear film status in congenital aniridia indicates a supportive treatment window.
Fabian Norbert FriesKayed MoslemaniTor Paaske UtheimBerthold SeitzBarbara Käsmann-KellnerNeil S LagaliPublished in: The British journal of ophthalmology (2022)
Ocular surface damage and dry eye signs appear in congenital aniridia regardless of mutation, appearing after 10 years of age and progressing thereafter. An early treatment window may exist for therapies to protect the ocular surface homoeostasis and limbal function, to possibly delay keratopathy development and progression.