A genetic model for multimorbidity in young adults.

Sarah L VollSpencer Van MilJustin GraffiElemi BreetveltMaria CorralErik BootEva W C ChowMarcos SanchesAmol A VermaAnne Susan Bassett

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2019)

The results indicate that adults with 22q11.2DS have a significant burden of illness with levels of multimorbidity comparable with those of the general population several decades older. In younger adults with multimorbidity, certain disease patterns may help identify genetic disorders in "big data."

Keyphrases

big data
young adults
artificial intelligence
machine learning
genome wide
copy number
risk factors
community dwelling
middle aged
dna methylation
childhood cancer