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The Differential Expression of Core Genes in Nucleotide Excision Repair Pathway Indicates Colorectal Carcinogenesis and Prognosis.

Jingwei LiuHao LiLiping SunXue FengZhen-Ning WangYuan YuanChengzhong Xing
Published in: BioMed research international (2018)
ERCC1, ERCC2, ERCC4, ERCC5, and DDB2 were differently expressed in CRC and normal tissues; ERCC2, ERCC3, ERCC5, XPA, and DDB2 correlated with clinicopathological parameters of CRC, while ERCC2, ERCC4, and XPC might predict CRC prognosis.
Keyphrases
  • dna repair
  • dna damage
  • genome wide
  • dna methylation
  • oxidative stress