Substrate stiffness promotes dentinogenesis via LAMB1-FAK-MEK1/2 signaling axis.
Mingru BaiHuiyu ChenZhaowei ZhangXiaoyu LiuDemao ZhangChengling WangPublished in: Oral diseases (2022)
The present study suggests odontoblast behaviors can be directly regulated by mechanical factors at cell-material interfaces, which offers fundamental mechanism in remodeling cell microenvironment, thereby contributing to physiological phenomena explanation and tissue engineering progress.