Blood Group Antigen Matching Influence on Gestational Outcomes (AMIGO) study.
Meghan DelaneyAgneta WikmanLeo van de WateringHenk SchonewilleJennie P VerdoesStephen P EmeryMichael F MurphyJulie StavesSusanne FlachDonald M ArnoldRichard M KaufmanAlyssa ZimanSarah K HarmMark FungCatherine S EppesNancy M DunbarAndreas S BuserErin MeyerHelen SavoiaPadmakumari AbeysingheNancy HeddleAlan TinmouthAicha N TraoreMark H Yazernull nullPublished in: Transfusion (2017)
The causal stimulus of antibodies that cause HDFN is predominantly from previous pregnancy. Although extended RBC matching for FCPs may impart some protection from allosensitization, we were unable to show a positive effect, possibly because matching policies are not uniform and there was a small number of mothers who previously received transfusions.