Hepatic stellate cells contribute to liver regeneration through galectins in hepatic stem cell niche.

Jian-Yun GeYun-Wen ZhengTomonori TsuchidaKinji FuruyaHiroko IsodaHideki TaniguchiNobuhiro OhkohchiTatsuya Oda

Published in: Stem cell research & therapy (2020)

Our findings, for the first time, demonstrated that galectins from activated HSCs contribute to hepatic stem cell expansion during liver regeneration, suggesting that galectins serve as important stem cell niche components.

Keyphrases

stem cells
induced apoptosis
cell therapy
cell cycle arrest
cell death
pi k akt