Long-term effects of adjuvant treatment for breast cancer on carotid plaques and brain perfusion.
Vincent KoppelmansKimberly D van der WillikBerthe M P AlemanFlora E van LeeuwenMaryam KavousiBanafsheh ArshiMeike W VernooijM Arfan IkramSanne B SchagenPublished in: Breast cancer research and treatment (2020)
On average two decades post-diagnosis, breast cancer survivors had lower tCBF and brain perfusion than cancer-free women. Also, survivors with a larger area of the carotid artery within the radiation field had a larger IMT. Future studies should confirm if these cerebrovascular changes underlie the frequently observed cognitive problems in cancer survivors.
Keyphrases
- resting state
- young adults
- white matter
- childhood cancer
- contrast enhanced
- papillary thyroid
- mental health
- early stage
- polycystic ovary syndrome
- functional connectivity
- cerebral ischemia
- current status
- squamous cell
- breast cancer risk
- computed tomography
- pregnancy outcomes
- magnetic resonance
- squamous cell carcinoma
- magnetic resonance imaging
- pregnant women
- insulin resistance
- combination therapy
- brain injury
- replacement therapy
- subarachnoid hemorrhage