25-Hydroxyvitamin D, Vitamin D Binding Protein and Gestational Diabetes Mellitus: A Two-Sample Mendelian Randomization Study.

Yiwen QiuDiliyaer AiniwanYe HuangLibi ZhangHaoyue Cheng Xialidan AlifuHaibo ZhouNuo XvBoya WangShuhui WangZexin ChenHui LiuDanqing ChenYunxian Yu

Published in: Nutrients (2024)

According to this study, a weak negative causal association between 25(OH)D and GDM risk was found, while we had little proof to support the link between VDBP and GDM. To further explore whether total or free 25(OH)D levels and GDM are causally related, GWAS data with an emphasis on women of reproductive age and other ethnic groups are required.

Keyphrases

binding protein
pregnant women
pregnancy outcomes
machine learning
metabolic syndrome
electronic health record
insulin resistance
data analysis