The tumour microenvironment is immuno-tolerogenic and a principal determinant of patient outcome in EBV-positive diffuse large B-cell lymphoma.

Colm KeaneJoshua TobinJay GunawardanaSantiyagu FrancisGrace GiffordSara GabrielliAnthony GillWilliam StevensonDipti TalaulikarClare GouldSanjiv JainSimone BirchMark HertzbergMaher K Gandhi

Published in: European journal of haematology (2019)

In EBV-pos DLBCL, the TME is immuno-tolerogenic and may explain the poor outcomes seen in this subtype of DLBCL.

Keyphrases

diffuse large b cell lymphoma
dendritic cells
epstein barr virus
regulatory t cells
immune response
case report
stem cells
type diabetes
skeletal muscle
metabolic syndrome
weight loss
adipose tissue