Using tumor habitat-derived radiomic analysis during pretreatment 18 F-FDG PET for predicting KRAS/NRAS/BRAF mutations in colorectal cancer.

Hongyue ZhaoYexin SuYan WangZhehao LyuPeng XuWenchao GuLin TianPeng Fu

Published in: Cancer imaging : the official publication of the International Cancer Imaging Society (2024)

The habitat-derived radiomic features were found to be helpful in stratifying the status of KRAS/NRAS/BRAF in CRC patients. The approach proposed here has significant implications for adjuvant treatment decisions in patients with CRC, and needs to be further validated on a larger prospective cohort.

Keyphrases

wild type
end stage renal disease
climate change
pet ct
chronic kidney disease
ejection fraction
newly diagnosed
positron emission tomography
early stage
prognostic factors
peritoneal dialysis
metastatic colorectal cancer
patient reported outcomes