Different cortical excitability profiles in hereditary brain iron and copper accumulation.
Raffaele DubbiosoLucia RuggieroMarcello EspositoPaola TarantinoMarcello De AngelisFrancesco ArutaSabina PappatàLorenzo UggaAlberto PipernoRaffaele IorioLucio SantoroRosa IodiceFiore ManganelliPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)
Hereditary conditions due to overload of copper and iron exhibited peculiar cortical excitability profiles that can help during differential diagnosis between these conditions. Moreover, such results can give us more clues about the role of metals in acquired neurodegenerative disorders, such as Parkinson disease, Alzheimer disease, and multiple sclerosis.