Tau maturation in the clinicopathological spectrum of Lewy body and Alzheimer's disease.
Sanaz ArezoumandanKatheryn Alexandra Quilico CousinsDaniel T OhmMaKayla LoweMin ChenJames GeeJeffrey S PhillipsCorey T McMillanKelvin C LukAndres DeikMeredith A SpindlerThomas F TropeaDaniel WeintraubDavid A WolkMurray GrossmanVirginia LeeAlice S Chen-PlotkinEdward B LeeDavid John IrwinPublished in: Annals of clinical and translational neurology (2024)
Mature tau may be more closely related to beta-amyloidosis than alpha-synucleinopathy, and pathophysiological processes of tangle maturation may influence the clinical features of dementia in mixed Lewy-Alzheimer's pathology.