Evaluation of response to neoadjuvant chemotherapy in osteosarcoma using dynamic contrast-enhanced MRI: development and external validation of a model.

Gijsbert M KalisvaartThomas Van Den BergheWillem GrootjansMaryse LejolyWouter C J HuysseJudith V M G BovéeDavid CreytensHans GelderblomFrank M SpeetjensLore LapeireMichiel A J van de SandeGwen SysLioe-Fee de Geus-OeiKoenraad L VerstraeteJohan L Bloem

Published in: Skeletal radiology (2023)

In this study, a relative wash-in rate of <2.3 determined with the whole slab segmentation method predicted histological response to neoadjuvant chemotherapy in osteosarcoma. Consistent performance was observed in an external test cohort.

Keyphrases

neoadjuvant chemotherapy
locally advanced
lymph node
sentinel lymph node
magnetic resonance imaging
deep learning
rectal cancer
squamous cell carcinoma
radiation therapy
computed tomography
magnetic resonance