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4-Mercaptobenzoic acid as a MALDI matrix for highly sensitive analysis of metals.

Qianqian SunShasha ZhangWeini HuangRan WangZihan ChenZongwei CaiZian Lin
Published in: The Analyst (2021)
4-Mercaptobenzoic acid (MBA) is introduced as a matrix for laser desorption/ionization time-of-flight mass spectrometry (MS) analysis of metals, exhibiting matrix-interference-free background, greatly enhanced MS signal intensity, and excellent reproducibility. The developed method was successfully extended for the rapid screening and sensitive determination of ultratrace metals in fine particulate matter (PM2.5).
Keyphrases
  • particulate matter
  • air pollution
  • mass spectrometry
  • human health
  • health risk
  • health risk assessment
  • multiple sclerosis
  • ms ms
  • heavy metals
  • molecularly imprinted
  • risk assessment
  • liquid chromatography
  • high intensity