Pharmacokinetic and pharmacodynamic properties of orally administered torsemide in healthy horses.

Gustavo F AgneSeung Woo JungAnne A WooldridgeSusan H DuranWilliam RavisRamiro Toribio

Published in: Journal of veterinary internal medicine (2018)

PO administered torsemide (4 mg/kg/day) successfully reached therapeutic concentrations in blood, induced clinically relevant diuresis, and resulted in moderate pre-renal azotemia and electrolyte disturbances.

Keyphrases

high glucose
diabetic rats
ionic liquid
drug induced
oxidative stress