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Dipeptidyl peptidase 4 inhibitors vs. metformin for new-onset dementia: a propensity score-matched cohort study.

Siyang LiuHeng WanSheng NieHuanyi CaoLan LiuHua LiangHong XuBicheng LiuChun-Bo ChenHuafeng LiuQiongqiong YangHua LiYaozhong KongGuisen LiQijun WanYan ZhaYing HuGang XuYongjun ShiYilun ZhouGuobin SuYing TangMengchun GongAixin GuoJianping WengHongjiang WuFan Fan HouJie Shen
Published in: The Journal of clinical endocrinology and metabolism (2024)
In this real-world study, we found that DPP4 inhibitors presented an association with a lower risk of dementia in individuals with type 2 diabetes than metformin, particularly in older people and those without diabetes-related comorbidities.
Keyphrases
  • mild cognitive impairment
  • cognitive impairment
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • adipose tissue
  • skeletal muscle