Effect of Intranasally Delivered rh-VEGF165 on Angiogenesis Following Cerebral Hypoxia-Ischemia in the Cerebral Cortex of Newborn Piglets.

Amit JainPanagiotis KratimenosIoannis KoutroulisAmishi JainAmulya BuddhavarapuJahan Ara

Published in: International journal of molecular sciences (2017)

Intranasal rh-VEGF165 may prevent the HI-induced decrease in the vascular density of the brain and could serve as a promising adjuvant therapy for hypoxic-ischemic encephalopathy (HIE).

Keyphrases

endothelial cells
high glucose
vascular endothelial growth factor
subarachnoid hemorrhage
cerebral ischemia
resting state
early stage
functional connectivity
brain injury
diabetic rats
white matter
early onset
cerebral blood flow
drug induced
blood brain barrier
multiple sclerosis
oxidative stress