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Comprehensive genetic structure analysis of Han population from Dalian City revealed by 20 Y-STRs.

Atif AdnanKaidirina KasimuAllah RakhaGuanglin HeTongya YangChuan-Chao WangJie LuJin-Feng Xuan
Published in: Molecular genetics & genomic medicine (2020)
Multidimensional scaling (MDS) analysis based upon pairwise Rst genetic distance showed difference among Han population from the east to the west and from the north to the south. We also predicted haplogroups using Y-STR haplotypes, which showed the dominance of Haplogroup O (65.2%) followed by Haplogroup C (14.5%) in Dalian Han population. Moreover, we found 10 individuals showed a null allele at the DYS448 in our samples. We also performed linear discriminatory analysis (LDA) between Han and other prominent Chinese minority ethnic groups. We presented Y-STRs data in the Y-Chromosome Haplotype Reference Database (YHRD) for the future forensic and other usage.
Keyphrases
  • mitochondrial dna
  • copy number
  • genome wide
  • emergency department
  • dna methylation
  • current status
  • big data
  • tertiary care
  • deep learning
  • data analysis
  • neural network