Polymorphisms in gene UGT1A1 modify the association of prenatal exposure to polycyclic aromatic hydrocarbons with congenital heart diseases risk.

Jing TaoNana LiZhen LiuYing DengXiaohong LiFangfang LuoXiaoyan LiPing YuJun Zhu

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2023)

rs4148323 may modify the association between prenatal PAHs exposure and CHDs risk. This finding needs to be further confirmed in a larger-scale study.

Keyphrases

polycyclic aromatic hydrocarbons
pregnant women
genome wide
gene expression
heavy metals
copy number