Detection of prostate cancer with 18F-DCFPyL PET/CT compared to final histopathology of radical prostatectomy specimens: is PSMA-targeted biopsy feasible? The DeTeCT trial.
Yves J L BodarB H E JansenJ P van der VoornG J C ZwezerijnenD MeijerJ A NieuwenhuijzenR BoellaardN H HendrikseO S HoekstraR J A van MoorselaarD E Oprea-LagerA N VisPublished in: World journal of urology (2020)
When comparing the PCa-localisation on 18F-DCFPyL-PET/CT with the RARP specimens, an accurate per-patient detection (93%) and localisation of csPCa was found. Thus, 18F-DCFPyL-PET/CT potentially allows for accurate PSMA-targeted biopsy.
Keyphrases
- pet ct
- radical prostatectomy
- prostate cancer
- fine needle aspiration
- ultrasound guided
- positron emission tomography
- loop mediated isothermal amplification
- cancer therapy
- real time pcr
- high resolution
- clinical trial
- study protocol
- case report
- phase iii
- phase ii
- drug delivery
- computed tomography
- sensitive detection
- open label
- quantum dots