Interplay of m 6 A and histone modifications contributes to temozolomide resistance in glioblastoma.

Fuxi LiSiyun ChenJiaming YuZhuoxing GaoZhangyi SunYang YiTeng LongChuanxia ZhangYuzhe LiYimin PanChaoying QinWenyong LongQing LiuWei Zhao

Published in: Clinical and translational medicine (2022)

A RNA modification and histone modification in TMZ resistance and emphasize the therapeutic potential of targeting the SOX4/EZH2/METTL3 axis in the treatment of TMZ-resistant GBM.

Keyphrases

dna methylation
stem cells
transcription factor
long non coding rna
combination therapy
nucleic acid