P129, a pyrazole ring-containing isolongifolanone-derivate: synthesis and investigation of anti-glioma action mechanism.
Yining JiangYunyun WangLiyan ZhaoWenzhuo YangLin PanYang BaiYubo WangYunqian Li
Published in: Discover. Oncology (2024)
The pyrazole ring-containing isolongifolanone derivate P129 exhibited promising anti-glioma activity by targeting CDK-2 and promoting apoptosis, indicating its potential importance as a new chemotherapeutic option for glioma.