MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility.

Yves J R MenezoPasquale PatrizioSilvia AlvarezEdouard AmarMichel BrackCharles BramiJacques ChouteauArthur ClementPatrice ClementMarc CohenDominique CornetBrian DaleGuiseppe D' AmatoLaetitia Jacquesson-FournolsPierre MaresPaul NeveuxJean Clement SageEdouard ServyTo Minh HuongGeraldine Viot

Published in: Journal of assisted reproduction and genetics (2021)

Determination of MTHFR SNPs in both men and women must be seriously advocated in the presence of long-standing infertility; male gametes, from MTHFR SNPs carriers, are not exempted from exerting a hazardous impact on fertility. Patients should be informed of the pleiotropic medical implications of these SNPs for their own health, as well as for the health of future children.

Keyphrases

end stage renal disease
healthcare
ejection fraction
genome wide
public health
chronic kidney disease
mental health
peritoneal dialysis
young adults
patient reported outcomes
type diabetes
climate change
current status
health information
skeletal muscle
social media
solid phase extraction
molecularly imprinted