Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway.
Fan FanRui WangDelphine R BoulbesHuiyuan ZhangStephanie S WatowichLing XiaXiangcang YeRajat BhattacharyaLee M EllisPublished in: PloS one (2018)
LPS-activated macrophages play an active role in promoting the CSC phenotype through activation of the SHH-Gli signaling pathway in CRC cells.