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High-dose post-transplant cyclophosphamide impairs γδ T-cell reconstitution after haploidentical haematopoietic stem cell transplantation using low-dose antithymocyte globulin and peripheral blood stem cell graft.

Nicolas StockerBéatrice GauglerMyriam LabopinAgathe FargeYishan YeLaure RicardEolia BrissotRemy DulérySimona SestiliGiorgia BattipagliaClémence MédiavillaAnnalisa PaviglianitiAnne BanetZoe Van De WyngaertTounes LedraaMohamad MohtyFlorent Malard
Published in: Clinical & translational immunology (2020)
Immunological reconstitution of γδ T cells is significantly delayed after Haplo-HCT using PTCy and low-dose ATG and is associated with an increased risk of increase in EBV viral load.
Keyphrases
  • high dose
  • stem cell transplantation
  • low dose
  • peripheral blood
  • stem cells
  • epstein barr virus
  • diffuse large b cell lymphoma
  • cell therapy
  • signaling pathway