Poor Inter-test Reliability Between CK18 Kits as a Biomarker of NASH.
Carolina Frade Magalhães Girardin Pimentel MotaZhenghui G JiangTakeshi OtsuboLinda FeldbrüggeTracy L ChalliesImad NasserSimon RobsonNezam AfdhalMichelle LaiPublished in: Digestive diseases and sciences (2015)
Measurements from two different CK18 M30 test kits did not correlate with each other. One kit showed statistically significantly higher levels of CK18 M30 in patients with advanced fibrosis and NASH, while the other kit did not. With the increasing use of CK18 as a biomarker in NASH, it is important to standardize the different kits as it could greatly bias the results.
Keyphrases