123I-mIBG scintigraphy in neuroblastoma: development of a SIOPEN semi-quantitative reporting ,method by an international panel.
Valerie LewingtonB LambertU PoetschgerZ Bar SeverF GiammarileA J B McEwanRita CastellaniT LynchB ShulkinM DrobicsA StaudenherzR LadensteinPublished in: European journal of nuclear medicine and molecular imaging (2016)
The SIOPEN mIBG score method is reproducible across the full spectrum of disease in high risk neuroblastoma. Numerical assessment of skeletal disease extent avoids subjective evaluation of uptake intensity. This robust approach provides a reliable means with which to examine the role of 123I mIBG scintigraphy as a prognostic indicator in neuroblastoma.