Energetics and clinical factors for the time required to walk 400 m: The Study of Muscle, Mobility and Aging (SOMMA).
Steven R CummingsLi-Yung LuiNancy W GlynnTheresa MauPeggy M CawthonStephen B KritchevskyPaul M CoenBret GoodpasterDavid J MarcinekRussell T HeppleSheena PatelAnne B NewmanPublished in: Journal of the American Geriatrics Society (2024)
Lower mitochondrial energetics is associated with needing more time to walk 400 m. This supports the value of developing interventions to improve mitochondrial energetics. Additionally, doing more moderate-to-vigorous exercise, increasing leg power, reducing weight, treating hip and knee stiffness, and screening for and treating anemia may reduce the time required to walk 400 m and reduce the risk of mobility disability.