Drug-Drug Interactions With Cyclosporine in the Anti-Hepatitis C Viral PrOD Combination Regimen of Paritaprevir/Ritonavir-Ombitasvir and Dasabuvir in Organ Transplant Recipients With Severe Hepatic Fibrosis or Cirrhosis.
Ying-Yu HuangYu-Hsuan HuangTsai-Hung WuChe-Chuan LoongChia-Chen HsuYueh-Ching ChouYuh-Lih ChangPublished in: Therapeutic drug monitoring (2022)
Although the combination with PrOD significantly affects the pharmacokinetics of CsA, it is effective and safe with regular monitoring of the CsA blood concentrations and appropriate CsA dose adjustment.