Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification Among Patients With Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-income Countries.
Kathryn DupnikVanessa R RiveraNancy DorvilYanique DuffusHanane AkbarnejadYipeng GaoJingyi LiuAlexandra ApollonEmelyne DumontCynthia RivierePatrice SevereKerlyne LavoileMaria Alejandra Duran MendicutiSamuel PierreVanessa RouzierKathleen Frances WalshAnthony L ByrnePatrice JosephPierre-Yves CremieuxJean William PapeSerena P KoenigPublished in: Open forum infectious diseases (2024)
CRP concentrations can be used to improve TB risk stratification, facilitating same-day decisions about ART initiation. Depending on the CRP threshold, one-quarter to two-thirds of patients could be eligible for same-day ART, with a reduction of 3- to 20-fold in the proportion with untreated TB, compared with a strategy of same-day ART while awaiting TB test results.
Keyphrases
- mycobacterium tuberculosis
- antiretroviral therapy
- hiv infected
- end stage renal disease
- hiv aids
- hiv positive
- human immunodeficiency virus
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- hepatitis c virus
- hiv testing
- men who have sex with men
- south africa
- sleep quality
- electronic health record
- patient reported
- drug induced