Rabeprazole has efficacy per se and reduces resistance to temozolomide in glioma via EMT inhibition.

Deepak BabuAnwita MudirajNeera YadavChandrashekhar Y B V KManas PanigrahiPhanithi Prakash Babu

Published in: Cellular oncology (Dordrecht) (2021)

Our data revealed (i) a clinical association of the EMT-like process with glioma malignancy and a poor survival and (ii) an anticancer and temozolomide sensitizing effect of rabeprazole by repressing EMT.

Keyphrases

epithelial mesenchymal transition
newly diagnosed
signaling pathway
single cell
machine learning