Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players.
Monica T LyFatima Tuz-ZahraYorghos TripodisCharles H AdlerLaura J BalcerCharles B BernickHenrik ZetterbergKaj BlennowElaine R PeskindRhoda AuSarah J BanksWilliam B BarrJennifer V WetheMark W BondiLisa M Delano-WoodRobert C CantuMichael J ColemanDavid W DodickMichael D McCleanJesse B MezJoseph PalmisanoBrett MartinKaitlin HartlageAlexander P LinInga K KoerteJeffrey L CummingsEric M ReimanMartha E ShentonRobert A SternSylvain BouixMichael L Alosconull nullPublished in: Neurology (2023)
and diffusion tensor imaging indices of white matter integrity showed stronger associations with WMH in the former football players. FLAIR WMH may have specific risk factors and pathologic underpinnings in RHI-exposed individuals.