Normal Alpha-Fetoprotein Hepatocellular Carcinoma: Are They Really Normal?
Chao-Wei LeeHsin-I TsaiWei-Chen LeeShu-Wei HuangCheng-Yu LinYi-Chung HsiehTony KuoChun-Wei ChenMing-Chin YuPublished in: Journal of clinical medicine (2019)
N-HCC patients were significantly older and had less hepatitis virus infections or cirrhosis. Their tumors tended to be smaller, less vascular invaded, and well-differentiated. The carcinogenesis of N-HCC may thus not be identical to that of typical HCC. GPC3 would be a promising tumor marker for diagnosing N-HCC. Further study is warranted to validate our findings.