The Prevalence of Acute Respiratory Distress Syndrome (ARDS) and Outcomes in Hospitalized Patients with COVID-19-A Study Based on Data from the Polish National Hospital Register.
Mariusz GujskiWaldemar WierzbaDaniel RabczenkoPaweł GoryńskiGrzegorz JuszczykPublished in: Viruses (2022)
Acute respiratory distress syndrome (ARDS) is a serious complication of COVID-19. This study aimed to evaluate the prevalence of ARDS among patients hospitalized with COVID-19 in Poland as well as to characterize clinical outcomes in patients hospitalized with COVID-19-associated ARDS. This is a retrospective, secondary analysis of epidemiological data from 116,539 discharge reports on patients hospitalized with COVID-19 in Poland between March and December 2020. The overall prevalence of ARDS was 3.6%, respectively 2.9% among females, and 4.4% among males ( p < 0.001). Of the 4237 patients hospitalized with COVID-19-associated ARDS, 3764 deaths were reported (88.8%). Participants aged 60 years and over had more than three times higher odds of COVID-19-associated ARDS. Men had higher odds of COVID-19-associated ARDS than women (OR = 1.55; 95% CI: 1.45-1.65; p < 0.001). Patients with COVID-19 and diabetes had higher odds of COVID-19-associated ARDS (OR = 1.16; 95% CI: 1.03-1.30; p = 0.01). Among patients with COVID-19-associated ARDS, older age, male sex (OR = 1.27; 95% CI: 1.03-1.56; p = 0.02), and presence of cardiovascular diseases (OR = 1.26; 95% CI: 1.00-1.59; p = 0.048) were significantly associated with the risk of in-hospital death. Among patients hospitalized with COVID-19 in Poland, the prevalence of ARDS was relatively low, but the in-hospital mortality rate in patients with COVID-19-associated ARDS was higher compared to other EU countries.
Keyphrases
- acute respiratory distress syndrome
- coronavirus disease
- extracorporeal membrane oxygenation
- mechanical ventilation
- sars cov
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- cardiovascular disease
- ejection fraction
- risk factors
- respiratory syndrome coronavirus
- peritoneal dialysis
- healthcare
- prognostic factors
- intensive care unit
- emergency department
- coronary artery disease
- weight loss
- electronic health record
- machine learning
- adverse drug
- adipose tissue
- acute care
- glycemic control
- insulin resistance