MALDI mass spectrometry imaging unravels organ and amyloid-type specific peptide signatures in pulmonary and gastrointestinal amyloidosis.

Jan SchürmannJuliane GottwaldGeorg RottenaicherAndreas Tholey Christoph Roecken

Published in: Proteomics. Clinical applications (2021)

MALDI-IMS MSI adds a valuable analytical approach to diagnose and classify amyloid and the detection frequency of individual tryptic peptides is organ-/tissue-type specific.

Keyphrases

mass spectrometry
liquid chromatography
high resolution
high performance liquid chromatography
gas chromatography
pulmonary hypertension
capillary electrophoresis
tandem mass spectrometry
multiple myeloma
dna methylation
simultaneous determination
real time pcr
quantum dots