Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome.
Thozhukat SathyapalanZeeshan JavedEric S KilpatrickAnne-Marie CoadyStephen L AtkinPublished in: Clinical endocrinology (2016)
This study suggests that rimonabant CB-I blockade paradoxically raised VEGF and the cytokine IL-8 in obese women with PCOS that may have offset the potential benefit associated with weight loss.
Keyphrases
- vascular endothelial growth factor
- weight loss
- bariatric surgery
- polycystic ovary syndrome
- endothelial cells
- roux en y gastric bypass
- adipose tissue
- metabolic syndrome
- obese patients
- gastric bypass
- type diabetes
- glycemic control
- pregnant women
- body mass index
- pregnancy outcomes
- cervical cancer screening
- human health