Low mortality in vaccinated immunocompromised haematology patients infected with SARS-CoV-2.
Briony ShawJake ShorttMichael LowBenjamin RogersZane KaplanPasquale FedeleGareth Peter GregoryShahla VilcassimMichael GilbertsonGeorge GrigoriadisStephen OpatPublished in: Internal medicine journal (2022)
Coronavirus disease 2019 (COVID-19) infection in patients with haematological neoplasms has been associated with increased mortality; however, many studies in this patient group were reported early in the pandemic. The authors evaluated outcomes of COVID-19 infection in patients with haematological conditions following widespread vaccination, newer viral variants and increasingly effective antiviral therapies. A 4% mortality rate was found and contemporary risk factors for hospitalisation including older age, nonvaccination or partial COVID-19 vaccination status and infection with non-Omicron strain were identified.
Keyphrases
- sars cov
- coronavirus disease
- respiratory syndrome coronavirus
- cardiovascular events
- end stage renal disease
- chronic kidney disease
- risk factors
- ejection fraction
- newly diagnosed
- prognostic factors
- type diabetes
- copy number
- cardiovascular disease
- coronary artery disease
- intensive care unit
- dna methylation
- adipose tissue
- gene expression
- metabolic syndrome
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- respiratory failure