Changes in murine anorectum signaling across the life course.
S FidalgoB A PatelR N RansonM J SaffreyMark S YeomanPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
The decrease in nitrergic signaling with increasing age may contribute to the age-related fecal impaction and constipation previously described in this model by partially obstructing defecation.
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