Renin Trajectories and Outcome in Stable Heart Failure with Reduced Ejection Fraction (HFrEF) on Contemporary Therapy: A Monocentric Study from an Austrian Tertiary Hospital Outpatient Clinic.
Emilie HanSuriya PrausmüllerAnnika WeidenhammerGeorg SpinkaHenrike ArfstenPhilipp E BartkoGeorg GoliaschMartin HülsmannNoemi PavoPublished in: Journal of the renin-angiotensin-aldosterone system : JRAAS (2023)
Intriguingly, renin is not a good biomarker to indicate prognosis in HF, while renin trajectories over a 1-year period do not have an additional value. Rapid physiologic plasma renin variations, but also opposing effects of angiotensinogen-derived metabolites under presence of RAS blockade, might obscure the predictive ability of renin.