Imaging the distribution of iron oxide nanoparticles in hypothermic perfused tissues.

Hattie L RingZhe GaoAnirudh SharmaZonghu HanCharles LeeKelvin G M BrockbankElizabeth D GreeneKristi L HelkeZhen ChenLia H CampbellBradley WeegmanMonica DavisMichael TaylorSebastian GiwaGregory M FahyBrian WowkRoberto PagotanJohn C BischofMichael Garwood

Published in: Magnetic resonance in medicine (2019)

Using MRI, we were able to assess the distribution of IONPs throughout organs and VCAs varying in complexity. Additional studies are necessary to better understand this system and validate the calibration between T1 measurements and IONP concentration.

Keyphrases

iron oxide nanoparticles
high resolution
magnetic resonance imaging
gene expression
contrast enhanced
computed tomography
case control
diffusion weighted imaging
photodynamic therapy
mass spectrometry